Local media reported this week that his condition had deteriorated in recent days but the 65-year-old Tsvangirai refuted the claims in a post on twitter saying he was shocked to read that he was critically ill.
Zimbabwe's main opposition party says its leader is in a hospital in neighbouring South Africa as concerns rise over the health of Morgan Tsvangirai, who has dominated the opposition for close to two decades.
What is known about Tsvangirai's condition?Since revealing his ailment in 2016 Tsvangirai has lost considerable weight and appeared weakened in recently-released photographs. "Nelson Chamisa as the acting President".
Last month, he said it was time for the older generation to step back and make way for "new hands", raising prospects of leadership change.
Internecine feuding over Tsvangirai's success is threatening to tear the party apart ahead of crucial general elections in which new president Emmerson Mnangagwa has vowed a clean sweep.
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His supporters should "brace for the worst", a source told Reuters news agency.
The hospital where Mr Tsvangirai is being treated has so far made no public comments on the issue.
Mr Tsvangirai's illness has divided the MDC, with a number of party officials reportedly jockeying to succeed the former trade union activist.
Tsvangirai, 65, has been the MDC's figurehead since the party was founded almost 20 years ago.