After Kane put Spurs ahead, the visitors looked in control until referee Slavko Vincic showed Lloris a straight red for charging out of his penalty area and bringing down Lozano, who had broken through the Tottenham defence.
The late minute strike from de Jong ensured the home team avoided defeat in the game after Lloris fouled Lozano and was handed marching others by the referee. But we made it hard for ourselves by not finishing the game off.
It sounds insane considering that many football fans would give their right arm to see their team compete in the Champions League, but it simply doesn't look like Spurs can hack it on two fronts, and we're not even halfway into the season yet.
Mauricio Pochettino refused to blame Hugo Lloris despite the goalkeeper's sending-off nearly certainly costing Tottenham their place in the Champions League. "If someone wants to blame a person, it's myself to blame because I am responsible for the team". The problem is when you are so good, you dominate the game and create the chances and you can't kill the game.
If Tottenham boss Mauricio Pochettino thought Wednesday's match in Eindhoven was not a "must win" match, he'll certainly think differently about his club's next match in the Champions League against PSV in London on November 6.
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He continued: "If you didn't win following what happened then you don't deserve to be in the Champions League".
"You have the situation with Hugo, maybe unfair, but if you score more goals you are going to win the game". We didn't force it and that's why our feeling is so bad. But, just as against Inter Milan two weeks ago when they lost 2-1, Mark van Bommel's team could not protect their lead. "It was a must-win game and we didn't win it".
"The PSV fans were so, so disappointed with the performance of their own team, but it was like it was contagious". But we played to keep possession [towards the end] and not to be aggressive in the last third. You need to kill the game and kill the opponent when you have the possibility.
Tottenham Hotspur's chances of Champions League qualification took a massive blow after a late equaliser from PSV Eindhoven striker Luuk de Jong earned the Dutch side a draw. "If not, always in football you pay".
Mauricio Pochettino's side have been forced to play all of their home matches at Wembley this season, while their 61,559-capacity arena gets built.