Lukaku has returned to training ahead of the Manchester derby on Sunday and could feature in his country's final two Nations League matches against Iceland and Switzerland.
City are nine points clear of their rivals but Guardiola insisted a derby win would not kill off United's chances of challenging them for the title.
Pogba and Mendy have known each other since they were together as youngsters at Le Havre's youth academy and have maintained that friendship in Manchester.
"A team has good and bad moments and this moment they have confidence".
The national squad have become very close following their success at the 2018 World Cup.
"We have one more session tomorrow".
"We have to control the ball more and be clinical, that's the game we'll try to do".
"All derbies are special, I think in Spain there is more noise than here but special, special for everybody", he said. "But I don't think they think it is an easy match for them".
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"I expect a very hard game".
"United have the history and always they are there".
"We have to stop them in their attacks, there is a way to do it and the manager knows that".
He continued: "He [Lukaku] was training with the team this morning. We can't talk about luck because everyone makes their own luck but we gave them the victory".
"But if we keep conceding goals before the opposition there will be a day where we can not come back so we have to grow up in our approach, because is clear the team is growing up, but we have to grow up in our compactness and start matches well".
Nevertheless, Mourinho is still keen to get the striker back playing as soon as possible - and the Portuguese coach has hinted that Lukaku could be back available for Sunday's showdown against Pep Guardiola's league leaders.
"I am not living outside so I know it's important".