An quake with a magnitude of 4.8 hit an area north of Catania on the slopes of Mount Etna in Sicily early on Wednesday, damaging buildings and injuring about 30 people, officials said.
About 30 people suffered injuries, mostly from falling masonry as they fled from their homes, officials said.
Ten people have been injured in Italy after an quake triggered by Mount Etna rocked the region.
Italy's national institute for geophysics and vulcanology (INGV) counted more than 130 seismic shocks in the zone, with the strongest reaching a magnitude of 4.0. The epicentre was below the north of Catania, and the damage caused several families to spend the night in the streets. Two people were rescued from a collapsed building.
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One 80-year-old man was safely extracted from the rubble of his home, the Italian news agency ANSA said.
Pictures of damaged buildings have been posted on social media.
In recent days the eruption has been shooting volcanic ash, heavy smoke and lava which is flowing down an uninhabited side of the mountain.
Mount Etna, 3,300 meters high, is the biggest active volcano in Europe, with frequent eruptions recorded in the past 2,700 years.
However, the chief of Italy's Civil Protection, Angelo Borrelli, has said there was reason to expect the volcanic activity on Etna to calm down soon.